Base user's setup for ZBrush

First of all we need to setup hotkeys which help not to jump between menus and submenus. As 95% of time you’ll be using only brushes I would recomend to setup hotkeys for them.

I’m using next hotkeys for brushes, for example:

Keys between 1 and 9 for sculpt brushes
Shift + 1-3 for smooth brushes
Ctrl + 1-9 for materials

You can use my config as reference. Copy text below, save it to file as hotkeys.txt and import it in ZBrush by Preferences -> Hotkeys -> Load. Store your config before cloase zbrush, as it will not save it automatically.

//ZBrush Hotkeys
[BRUSH:MORE ITEMS,98] // B
[BRUSH:SMOOTH STRONGER,307] // Shift+3
[BRUSH:MOVE ELASTIC,5054565] // Popup+E
[BRUSH:MPOLISH,7151728] // Popup+P
[BRUSH:MASKCURVE,562] // Ctrl+2
[BRUSH:CLAYLINE,4399212] // Popup+L
[BRUSH:CLAYTUBES,50] // 2
[BRUSH:CLAY,51] // 3
[BRUSH:ID_POLISH,52] // 4
[BRUSH:CLAYBUILDUP,49] // 1
[BRUSH:MOVE TOPOLOGICAL,53] // 5
[BRUSH:MOVE,54] // 6
[BRUSH:STANDARD,55] // 7
[BRUSH:SMOOTH35,305] // Shift+1
[BRUSH:JACSMOOTHEDGER,306] // Shift+2
[MATERIAL:ID_LIGHTCLAY,1075] // Alt+3
[MATERIAL:MAH_MODELING_01,1074] // Alt+2
[MATERIAL:ID_WETCLAY,1076] // Alt+4
[MATERIAL:MATCAP GRAY,1073] // Alt+1
[BRUSH:DAMSTANDARD,56] // 8
[BRUSH:ORB_CRACKS1,48] // 0
[MATERIAL:FLAT COLOR,1079] // Alt+7
[MATERIAL:MAH_DIRTY_BLUE_01,822] // Ctrl+Shift+6
[MATERIAL:BASICMATERIAL,1077] // Alt+5
[BRUSH:AUTO MASKING:BACKFACEMASK,109] // M
[TRANSFORM:SOLO,1257] // Alt+�
[BRUSH:POLISH,5251120] // Popup+0
[BRUSH:MASKCURVEPEN,561] // Ctrl+1
[BRUSH:TRIMCURVE,817] // Ctrl+Shift+1
[BRUSH:CLIPCURVE,818] // Ctrl+Shift+2
[BRUSH:TRIMADAPTIVE,57] // 9
[MATERIAL:ID_GRAYCLAY,1078] // Alt+6